遺伝性乳癌卵巣癌 遺伝性乳癌卵巣癌 HBOC: Hereditary Breast and Ovarian Cancer 原因遺伝子 : BRCA1, BRCA2 BRCA: breast cancer susceptibility gene BRCA1 1994報告 24exons 1863amino acids BRCA2 1995報告 26exons 3418amino acids